Melvyn,
I just changed from a 21 to a 22 and have found the results as Beezageezauk describe. With the 21 it was uncomfortable staying in the high 30's in 3rd gear for typical driving on surface streets. It made for a lot of shifting to 4th when trying to get just a bit faster and then soon needing to downshift on the slightest speed reduction (many of the surface streets where I live are posted 40 MPH). Actually, when I was looking for a new sprocket, I was looking for a 23, but a 22 popped up on eBay, so I decided to try that. Considering what B'g'uk has said, and my increased riding comfort, I guess I made the correct choice, but I only have about 65 miles on the 22, so far.
Richard L.
P.S.
I looked at your band website and watched parts of the videos. The band seems like a lot of fun and, by the way, I live in the Chicago area. Also, once-upon-a-time, I played bass (not that well).