I found, with good points etc., and a new auto-advance I found no difference worth talking about, between strobe and fag paper timing, but if you never do strobe timing, you'll never really know what the timing is doing when running.
With a badly worn points pivot and a solid pinion, so it was fixed at full advance, the timing jumped from about 39 degrees to about 45, at something over 2000rpm. Quite scary!
At low rpm (and while setting timing with fag paper), I think the slop in the pivot was taken up before the points opened. At higher rpm, the points were getting knocked open instantly, through an inertia effect. That's what I theorised anyway.