Can be any number of reasons, Primary issues such as chain whip at certain RPMS/Speeds, worn thrust washers at back of clutch basket, bad clutch basket bearings or wear, clutch basket issues
(Go away when clutch lever pulled?) loose end nuts or not fully seated on either end of mainshaft? Worn bushes in trans?
(Klaus has a valid point about 4th gear final drive being a important clue) These issues can be challenging to nail down. Especially when you do your own work and know intimately all the little bits and pieces. Some call this "Knock-itis" and many a man has fallen to paranoia and rants chasing down real or perceived issues with noises and vibration like this. Some go off the deep end when after repeated tear downs the cause still is not found or determined. (Toys in the attic)
I have a family friend who spent a career working for several local Auto dealerships and much of the latter half of his career was customer service and complaint resolution. Patient and philosophical guy.
"Well, it makes this horrible clatter and the whole car shakes but it only does it going downhill and going over railroad tracks and most of the time only when turning left,. It did it a couple times turning right but that was a long time ago,. And most of the time its when its raining, when its dry out it doesnt seem to do it. When my husband drives it he has not had it happen at all which is just totally weird right? Am I right? What is with him anyway...? So, he just thinks I am crazy so thats why I brought my friend Becky with me today, she heard it too!"
I know a few people that motor about blissfully ignorant of this stuff and in some cases things go horribly wrong and catastrophic failures (You did not notice that your oil light was on and there was smoke coming out?) but some seem to just do quite well ignoring any such noises or symptoms and it all works out.